Evonik
Tuesday, December 6, 2022
4:00 p.m. CET / 10:00 a.m. EST

HPAPI process development and pilot-lab implementation

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Overview

Many HPAPIs require multiple process steps for synthesis, each of which must take worker safety into consideration while still delivering a robust process for scale-up. Join us as Dr. Adam Myers, Robert Farner and Jason Plassard discuss the safety and special process engineering capabilities required for such complex projects.

In the second webinar in our series, you can learn Evonik’s approach to implementing new HPAPI processes in our labs while assuring worker safety. Our speakers will walk you through a case study of a new chemical entity that was safely and successfully transferred into our development labs, further optimized, analyzed, and scaled to kilogram production. We will discuss the physical handling of the product during lab development and optimization, the analytical preparations and handling, and the design concepts of a kilo-scale facility.

This webinar is suitable for anyone in external HPAPI development outsourcing, procurement, engineering, EHS, industrial hygiene, project management, QC or analytical chemistry, who is interested in learning more about HPAPI handling in laboratory settings.

Key learnings for participants of this webinar:
  • Case example of transfer of an HPAPI to development labs and kilo-scale production
  • Understanding of interplay between EHS, engineering, chemistry, analytical and quality for complex projects
  • HPAPI implications for analytical chemistry

Experts featuring this session

Jason Plassard
Quality Control Director
Evonik Health Care

Vita
For 10 years Jason has served as director of quality control at the Evonik Health Care site in Lafayette, Indiana, and has 30 years’ professional experience in the pharmaceutical industry.

He joined Evonik in 2011, bringing vast experience in project management and customer interaction to the fledgling CDMO organization. Jason has overseen tremendous growth within the analytical group in Indiana and was key in the implementation of the site’s highly successful Lean Laboratory initiative. His team is responsible for manufacturing support, new project implementation, and analytical development.

Jason holds a bachelor’s degree in chemistry from Purdue University. Prior to joining Evonik, he spent 18 years supporting the pharmaceutical industry in the field of bioanalysis.
Dr. Adam C. Myers
Senior Project Manager Drug Substance
Evonik Health Care

Vita
Adam has more than 17 years of experience in the pharmaceutical industry, including synthesis, contract analytical (cGMP and GLP), and contract manufacturing, with a focus on complex project management, commercial API manufacturing, and in vitro comparative analysis of drug substance and drug products.

Adam joined Evonik in 2020 as a Senior Project Manager in Drug Substance at Tippecanoe Laboratories.

Adam received both his B.S. in Honors Chemistry and Biochemistry and his Ph.D. in Organic Chemistry from Purdue University.

Adam also has held various leadership positions within the American Chemical Society at both the local and national levels, and serves as an ACS Career Consultant and Career Pathways Workshop facilitator.
Robert Farner
Production Manager Drug Substance
Evonik Health Care

Vita
Robert has over 30 years’ experience in the development, scale-up and optimization of processes for specialty chemicals, drug substances and intermediates. This includes work with highly potent APIs, acutely toxic materials, and highly reactive compounds. Robert also provided leadership for a project that converted a development facility into a GMP and HPAPI-capable kilo laboratory.

Robert’s current role as a production manager at Tippecanoe Laboratories provides ongoing challenges with first-time scaleup of highly potent compounds at 20 to 100 kg scale.

Robert holds a B. S. degree in Chemistry from Purdue University.

Related webinars in this series

This is the second webinar of our 3-part webinar series entitled "Handling HPAPIs: From toxicological risk assessment to metric ton manufacturing". Join us to follow the journey of a highly potent molecule, starting from toxicological assessment to initial tech transfer and development onto large scale (metric ton) commercial manufacture.

To learn more about the two other webinars in this series please click on the respective webinar below. To register for multiple webinars of this series simply select them in the registration form.

  • Evaluating toxicological risk along the product lifecycle of an HPAPI – a CDMO perspective
    Tuesday, November 15, 2022 | 10:00 AM (EST) / 4:00 PM (CET)

  • Manufacturing metric tons of HPAPIs: what does success look like?
    Tuesday, January 24, 2023 | 10:00 AM (EST) / 4:00 PM (CET)

Register now

Details

Webinar language
English

Venue

Online

Questions?

Julia Born
Market Communications Health Care
+49 6151 18 4984 E-Mail
Register now
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