Reformulation strategies for oral drug products

Overview

Many reformulation strategies pursued by pharmaceutical companies for oral dosage forms are based upon the modification of the original product’s drug release profile. Functional excipients can also help to reformulate an existing product into superior dosage forms such as sustained release multiparticulates and matrix tablets to improve performance, and reduce dosage frequency, or to further improve solubility and reduce drug load. Reformulation strategies and case studies covering these topics will be presented.

Experts featuring this session

Dr. Nitesh Shah
Formulation & Application Services Manager
Vita

Dr. Nitesh Shah is serving as Head of Formulation & Application Services of Asia South for the Health Care division of Evonik Industries. He heads 3 technical services labs of India, Bangladesh & Thailand; and is responsible for providing technical support to South Asia, SEA & Pakistan. Nitesh joined Evonik in September 2012 as Manager-Technical Services.

Nitesh started his career as Trainee in NDDS department of Zydus Cadila (Ahmedabad, India). He later joined as a lecturer in Zundal Pharmacy College (Ahmedabad).

Prior to joining Evonik he worked with NCE formulation development of Johnson & Johnson (Mumbai, India).

Nitesh received his Masters and Ph.D. degree in Pharmaceutical Sciences from Nirma University, Ahmedabad, India. He has 11 publications in international peer reviewed journals and presented his research work at several national and international seminar & conferences.

Nitesh holds expertise in Encapsulation, HME, Spray drying, QbD & GMP.

Dr. Nitesh is a renowned speaker in academic and industry workshops on Excipients, Oral Drug Delivery, Complex Parenteral Drug Delivery & Formulation Development Advances in Pharmaceutical Industry.

Dr. Jessica Müller-Albers
Strategic Marketing Director
Evonik Health Care
Vita

Dr. Jessica Müller-Albers joined Evonik’s Health Care business line in 2010 and is currently working as Strategic Marketing Director for oral solutions.

Before taking over the current position she was group leader for drug delivery where she focused on the development and analytics of new oral and parenteral platform technologies for the pharma and food industry as well as the development of cell culture media.

She held different positions in application service and formulation development of oral excipients and worked for a contract manufacturer where she gained experience in developing solid and semi-solid dosage forms, product transfer, manufacturing of clinical-trial medication, GMP and high potent handling.

She received her degree in pharmacy from the University of Halle/Saale and her Ph.D. from the University of Duesseldorf where she specialized on melt extrusion of poorly soluble drugs.

Moreover, she authored several research papers, book chapters and patents.