Reformulation strategies for oral drug products

Overview

Many reformulation strategies pursued by pharmaceutical companies for oral dosage forms are based upon the modification of the original product’s drug release profile. Functional excipients can also help to reformulate an existing product into superior dosage forms such as sustained release multiparticulates and matrix tablets to improve performance, and reduce dosage frequency, or to further improve solubility and reduce drug load. Reformulation strategies and case studies covering these topics will be presented.

Experts featuring this session

Dr. Nitesh Shah
Business Director, Asia South
Evonik Health Care
Vita

Dr. Nitesh Shah joined Evonik in 2012 as Manager-Technical Services for North India & Gujarat. In subsequent years he handled position of increasing responsibilities in Technical Services. He was later entrusted with responsibility of Business Development & Key Account Sales.

Currently he serves as Business Director of Asia South, where he is responsible for overall business of Asia South for all functions of Sales, Technical, Marketing, Business Development, Customer Service & Logistics.

Nitesh started his career as a Lecturer in Pharmacy college in Ahmedabad in 2007 and later worked in Formulation development of generics and NDA’s with companies like Zydus Cadila; and Johnson & Johnson.

Nitesh received his Masters and Ph.D. degree in Pharmaceutical Sciences from Nirma University, Ahmedabad, India. He has 13 publications in international peer reviewed journals.

Dr. Jessica Müller-Albers
Strategic Marketing Director
Evonik Health Care
Vita

Dr. Jessica Müller-Albers joined Evonik’s Health Care business line in 2010 and is currently working as Strategic Marketing Director for oral solutions.

Before taking over the current position she was group leader for drug delivery where she focused on the development and analytics of new oral and parenteral platform technologies for the pharma and food industry as well as the development of cell culture media.

She held different positions in application service and formulation development of oral excipients and worked for a contract manufacturer where she gained experience in developing solid and semi-solid dosage forms, product transfer, manufacturing of clinical-trial medication, GMP and high potent handling.

She received her degree in pharmacy from the University of Halle/Saale and her Ph.D. from the University of Duesseldorf where she specialized on melt extrusion of poorly soluble drugs.

Moreover, she authored several research papers, book chapters and patents.