Long-acting, complex drug delivery products, particularly those based on microparticles, nanoparticles and implants, are among the most attractive parenteral products in the pharmaceutical industry.Long-acting injectables that use bioresorbable polymers for systemic and local drug delivery have improved the lives of millions of patients globally, based on successful outcomes for the treatment of schizophrenia, diabetes, substance abuse, cancer, ocular, rare and hormonal diseases. These products have many advantages, such as simplifying the drug regimen by decreasing dosing frequency, helping to improve efficacy and treatment adherence.
In this fireside chat, Evonik’s drug delivery experts will share their experiences and insights on the discovery and development of long-acting injectables, presenting the most advanced polymer-based excipients, products and platforms on the market. They will highlight key properties of bioresorbable poly(lactide-co-glycolide) polymers and explain their relevance to drug delivery formulations.
In addition, our speakers will discuss GMP manufacturing considerations for both parenteral excipients and drug products. Key areas of focus will be product-by-process manufacturing, ocular implants, microparticles and nanoparticles.
The fireside chat creates a particularly interactive dialogue, engaging the audience to take part in polls and asking questions to the speakers.
What the audience will learn:
- Brief history of long acting injectables and polymeric drug products on the market
- Overview of key PLG properties and new polymers relevant to drug delivery formulations
- Recent application trends, including immuno-oncology and ocular drug delivery
- Challenges for GMP-production of implants, microparticles and nanoparticles
- Technology transfer and scale-up