Evonik
Tuesday, September 19, 2023

Brunch & Learn: Innovative Formulations for Nanomedicine

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Overview

New drug substances and modalities have been a driving force behind innovation in formulation development. This success could not have happened without decades of biotechnology research and the discovery of excipients and technologies to enable effective drug delivery.

In this seminar we take you through two key examples in innovative formulation development:

1- Lipids are one of the pillar excipients for drug delivery systems and are especially important for RNA-based therapies such as mRNA vaccines
2- Long-acting injectables, particularly those based on microparticles, nanoparticles and implants, are among the most attractive parenteral products in the pharmaceutical industry

This event will be hosted by Evonik Health Care, featuring talks from Dr. Ulrich Kloeckner and Dr. Tom Tice and. We are also delighte to welcome guest speaker Alejandro Mahía Moros from Certest, who will present drug delivery insights from the perspective of a pharmaceutical company.

Key learnings for participants:
  • Importance of control of lipid impurities and technologies needed for lipid manufacturing
  • Overview of poly(lactide-co-glycolide) polymer properties relevant to drug delivery formulations
  • History and backstories around long acting injectables and polymeric drug products on the market
  • Challenges in the GMP-production of implants, microparticles and nanoparticles.

Agenda

The workshop will start at 9:00 on Tuesday, September 19, 2023 and finish at 13:00 on the same day.

To see the detailed workshop program please click here.

Experts

Javier Palacin
Business Manager
Evonik Health Care

Dr. Thomas R. Tice
Senior Director Technical Global Technical Marketing
Evonik Health Care

Vita
Thomas Tice is internationally recognized for his research and product development of complex parenteral, drug delivery dosage forms based on bioabsorbable polymer excipients. He is known for his accomplishments involving injectable, extended-release microparticles made with bioabsorbable lactide/glycolide polymers designed for systemic and local drug delivery. He was a team leader and core inventor to develop the first commercial, injectable, extended-release microparticle product. This product, a one-month LHRH formulation indicated for the treatment of prostate cancer (Decapeptyl® SR), is still on the market today. He has also served on various US Pharmacopeia expert committees for 17 years, and is currently on the General Chapters Dosage Forms Expert Committee and Excipient Joint Committee.

At Evonik, Dr. Tice, provides scientific support to Evonik’s innovation, sales, product development, research, intellectual property and M&A teams. He earned his BSc in Chemistry and PhD in Biophysics from Syracuse University, New York. He held a postdoctoral fellow position at the University of Alabama at Birmingham (UAB) in Microbiology. He holds 48 US patents with many foreign equivalents and has more than 180 publications, presentations, and invited lectures to his credit. He flew experiments on two Space Shuttle flights.
George Smith
Business Manager
Evonik Health Care

Dr. Ulrich Klöckner
Global Project Manager
Evonik Health Care

Vita
Dr. Ulrich Klöckner joined Evonik in 2017 and has held several R&D roles within the Evonik Health Care business. In his first positions as a laboratory head he was responsible for the process development and scale up of APIs and lipids. As a project manager in the CDMO business, he managed and led projects focusing on APIs and lipids manufacturing under cGMP.

Since 2022, as a global project manager, Ulrich is responsible for the project management and serves as the technical contact of Evonik Health Care’s lipid business. Ulrich is an organic chemist by education and obtained his PhD from the University of Tuebingen in Germany. As a postdoctoral fellow, holding a DFG scholarship, he went to the University of Urbana Champaign in Illinois, USA. Ulrich is author of numerous research papers and patent applications.

Details

Participation fee:
Free of charge
City/State:
Barcelona
Country:
Spain
Seminar language:
English

Venue

The workshop will take place at:
Fundació Parc Científic de Barcelona
Campus Diagonal - Universitat de Barcelona
Baldiri Reixac 10-12
08028 Barcelona

Questions?

George Smith
Business Manager
Evonik Health Care
+44 7496 25 7839 E-Mail