Evonik
Monday, May 13, 2024

Scientific Symposium: Latest Advances in Lipid and LNP Development and Manufacturing

Sorry! This seminar has already taken place. Please see our event calendar for upcoming events.
Back to workshop overview

Overview

Lipids are some of the most clinically important excipients for drug delivery systems and are especially relevant for RNA-based therapies and mRNA vaccines. As a CDMO partner offering end-to-end solutions, Evonik has decades of experience and expertise in every step of the manufacturing process, including route scouting, process development and optimization, purification, isolation, characterization, scale-up, and commercialization.

This workshop will focus on the growth and use of lipids for drug delivery and provide insight into important steps for success. We will not only outline the role of our novel multivariate models to speed up timelines and increase successful scale-up and transfer to the clinic, but also highlight current advances in leveraging novel lipids, such as randomized PEGs (rPEGs) in LNP-based delivery systems.

Key learnings for participants
  • Introduction to capabilities necessary to support lipid development and manufacturing
  • Lipid impurities and their impact on therapeutic effectiveness
  • LNP formulation opportunities with rPEGs

Agenda

1:00 p.m.
Registration & welcome

Topics to be Covered: (Formal agenda to be shared closer to the date)
-Lipids, learnings & future opportunities
-From PEG to rPEGs: A unique building block in next generation lipid nanoparticles
-LNP Mixing Technologies and Key Considerations fora Successful Scale-Up
-Choosing the right lipid and adjuvant for your formulation
-and more!

5:00 p.m.
Reception & Cocktails

Experts

Dr. Michael Parr
Director Formulation and Process Development
Evonik Health Care

Vita
Dr. Michael “Mike” Parr joined the Production & Technology team of Evonik’s Health Care business line in 2021 as director of formulations and process development for the Vancouver site. Mike is responsible for leading multifunctional teams and ensuring the successful execution of a portfolio of complex customer-funded development programs as part of the parenteral drug delivery solutions business.

Mike has more than 20 years of experience in the pharmaceutical industry including roles at Sitka Biopharma, CDRD Ventures Inc., Angiotech and Biogen Idec. His areas of expertise include liposomal drug delivery systems, formulation, molecular biology, GLP, GMP activities and clinical development. Mike holds a B.Sc. Honours and Ph.D. in Biochemistry and Molecular Biology from The University of British Columbia in the laboratory of Dr. Pieter Cullis and he completed post-doctoral studies at Harvard Medical School.
Dr. Lars Geiger
Global Director Project Management Drug Substance
Evonik Health Care

Vita
Dr. Lars Geiger is Global Director of Project Management Drug Substance at Evonik’s Health Care product line. He has been working in Evonik’s pharma CDMO business line in different R&D and project management roles in Germany and the USA for more than 18 years.

Lars is organic chemist by training and received his diploma from the University of Cologne. He graduated at the University of Würzburg in 2004 in the group of Prof. Dr. Carsten Schmuck, in the field of bioorganic chemistry.

Afterwards, he conducted a postdoctoral stay at the Massachusetts Institute of Technology (MIT) in Boston, USA, in the group of Prof. Dr. Timothy M. Swager, where he worked on conduction polymers.

In his career he led various large pharma projects at Evonik including the development of the lipid production for BioNTech. In his current role, he is heading the customer project management organization in the drug product CDMO business, focusing on Active Pharmaceutical Ingredient (API) manufacturing.

Details

Participation fee:
$50
City/State:
Boston, MA
Country:
USA
Seminar language:
English

Venue

The workshop will take place at:
The Westin Copley Place, Boston
10 Huntington Ave
Boston, MA 02116

Questions?

Emily Peters
Manager Regional Marketing, North America
Evonik Health Care
+1 732 981 5145 E-Mail